Visualizing ocular lens fluid dynamics using MRI: Manipulation of steady state water content and water fluxes | Vaghefi, E.| Pontre, B.P.| Jacobs, M.D.| Donaldson, P.J. | 2011 | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 48 | 10.1152/ajpregu.00173.2011 |
Spatial localization of A2E in the retinal pigment epithelium | Grey, A.C.| Crouch, R.K.| Koutalos, Y.| Schey, K.L.| Ablonczy, Z. | 2011 | Investigative Ophthalmology and Visual Science | 44 | 10.1167/iovs.10-7020 |
Focus on Molecules: The cystine/glutamate exchanger (System xc-) | Lim, J.C.| Donaldson, P.J. | 2011 | Experimental Eye Research | 23 | 10.1016/j.exer.2010.05.007 |
Cryptococcus neoformans modulates extracellular killing by neutrophils | Qureshi, A.| Grey, A.| Rose, K.L.| Schey, K.L.| Del Poeta, M. | 2011 | Frontiers in Microbiology | 14 | 10.3389/fmicb.2011.00193 |
Cellular localization of glutamate and glutamine metabolism and transport pathways in the rat ciliary epithelium | Hu, R.G.| Lim, J.C.| Kalloniatis, M.| Donaldson, P.J. | 2011 | Investigative Ophthalmology and Visual Science | 8 | 10.1167/iovs.10-6422 |
Fatty acid uptake and incorporation into phospholipids in the rat lens | Nealon, J.R.| Blanksby, S.J.| Donaldson, P.J.| Truscott, R.J.W.| Mitchell, T.W. | 2011 | Investigative Ophthalmology and Visual Science | 2 | 10.1167/iovs.10-5830 |
Magnetic resonance and confocal imaging of solute penetration into the lens reveals a zone of restricted extracellular space diffusion | Vaghefi, E.| Walker, K.| Pontre, B.P.| Jacobs, M.D.| Donaldson, P.J. | 2012 | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 25 | 10.1152/ajpregu.00611.2011 |
Characterization of glutathione uptake, synthesis, and efflux pathways in the epithelium and endothelium of the rat cornea | Li, B.| Lee, M.S.| Lee, R.S.Y.| Donaldson, P.J.| Lim, J.C. | 2012 | Cornea | 18 | 10.1097/ICO.0b013e31823f76bd |
Molecule-specific imaging and quantitation of A2E in the RPE | Ablonczy, Z.| Gutierrez, D.B.| Grey, A.C.| Schey, K.L.| Crouch, R.K. | 2012 | Advances in Experimental Medicine and Biology | 15 | 10.1007/978-1-4614-0631-0_11 |
Development of a 3D finite element model of lens microcirculation | Vaghefi, E.| Malcolm, D.T.K.| Jacobs, M.D.| Donaldson, P.J. | 2012 | BioMedical Engineering Online | 10 | 10.1186/1475-925X-11-69 |
Alterations of glutamate, glutamine, and related amino acids in the anterior eye secondary to ischaemia and reperfusion | Hu, R.G.| Zhu, Y.| Donaldson, P.| Kalloniatis, M. | 2012 | Current Eye Research | 6 | 10.3109/02713683.2012.669509 |
Identification of a nonselective cation channel in isolated lens fiber cells that is activated by cell shrinkage | Gunning, S.J.| Chung, K.K.H.| Donaldson, P.J.| Webb, K.F. | 2012 | American Journal of Physiology - Cell Physiology | 4 | 10.1152/ajpcell.00237.2012 |
Fluid in equals fluid out-evidence for circulating fluid fluxes in the lens | Donaldson, P.J. | 2012 | Investigative Ophthalmology and Visual Science | 1 | 10.1167/iovs.12-11012 |
Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium | Ablonczy, Z.| Higbee, D.| Anderson, D.M.| Dahrouj, M.| Grey, A.C.| Gutierrez, D.| Koutalos, Y.| Schey, K.L.| Hanneken, A.| Crouch, R.K. | 2013 | Investigative Ophthalmology and Visual Science | 103 | 10.1167/iovs.13-12250 |
Antioxidant delivery pathways in the anterior eye | Umapathy, A.| Donaldson, P.| Lim, J. | 2013 | BioMed Research International | 30 | 10.1155/2013/207250 |
Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epithelium | Ablonczy, Z.| Higbee, D.| Grey, A.C.| Koutalos, Y.| Schey, K.L.| Crouch, R.K. | 2013 | Archives of Biochemistry and Biophysics | 27 | 10.1016/j.abb.2013.08.005 |
Mass spectrometry of membrane proteins: A focus on aquaporins | Schey, K.L.| Grey, A.C.| Nicklay, J.J. | 2013 | Biochemistry | 26 | 10.1021/bi301604j |
Verification and spatial localization of aquaporin-5 in the ocular lens | Grey, A.C.| Walker, K.L.| Petrova, R.S.| Han, J.| Wilmarth, P.A.| David, L.L.| Donaldson, P.J.| Schey, K.L. | 2013 | Experimental Eye Research | 22 | 10.1016/j.exer.2012.12.004 |
Molecular identification and cellular localization of a potential transport system involved in cystine/cysteine uptake in human lenses | Lim, J.C.| Lam, L.| Li, B.| Donaldson, P.J. | 2013 | Experimental Eye Research | 20 | 10.1016/j.exer.2013.09.002 |
A computer model of lens structure and function predicts experimental changes to steady state properties and circulating currents | Vaghefi, E.| Liu, N.| Donaldson, P.J. | 2013 | BioMedical Engineering Online | 11 | 10.1186/1475-925X-12-85 |
Molecular identification and cellular localisation of GSH synthesis, uptake, efflux and degradation pathways in the rat ciliary body | Li, B.| Umapathy, A.| Tran, L.U.| Donaldson, P.J.| Lim, J.C. | 2013 | Histochemistry and Cell Biology | 11 | 10.1007/s00418-012-1049-6 |
An exploration into diffusion tensor imaging in the bovine ocular lens | Vaghefi, E.| Donaldson, P.J. | 2013 | Frontiers in Physiology | 6 | 10.3389/fphys.2013.00033 |
A link between maternal malnutrition and depletion of glutathione in the developing lens: A possible explanation for idiopathic childhood cataract? | Kumar, D.| Lim, J.C.| Donaldson, P.J. | 2013 | Clinical and Experimental Optometry | 4 | 10.1111/cxo.12076 |
Reversing the age-dependent decline in lens transport: A new strategy to prevent age related nuclear cataract? | Donaldson, P. | 2013 | Investigative Ophthalmology and Visual Science | 2 | 10.1167/iovs.13-13394 |
Alzheimer's disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers | Chang, L.Y.L.| Lowe, J.| Ardiles, A.| Lim, J.| Grey, A.C.| Robertson, K.| Danesh-Meyer, H.| Palacios, A.G.| Acosta, M.L. | 2014 | Alzheimer's and Dementia | 63 | 10.1016/j.jalz.2013.06.004 |
The utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometry | Ablonczy, Z.| Smith, N.| Anderson, D.M.| Grey, A.C.| Spraggins, J.| Koutalos, Y.| Schey, K.L.| Crouch, R.K. | 2014 | Proteomics | 19 | 10.1002/pmic.201300406 |
Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lenses | Vorontsova, I.| Lam, L.| Delpire, E.| Lim, J.| Donaldson, P. | 2014 | Investigative Ophthalmology and Visual Science | 5 | 10.1167/iovs.14-15911 |
Active maintenance of the gradient of refractive index is required to sustain the optical properties of the lens | Vaghefi, E.| Kim, A.| Donaldson, P.J. | 2015 | Investigative Ophthalmology and Visual Science | 26 | 10.1167/iovs.15-17861 |
Spatial distributions of AQP5 and AQP0 in embryonic and postnatal mouse lens development | Petrova, R.S.| Schey, K.L.| Donaldson, P.J.| Grey, A.C. | 2015 | Experimental Eye Research | 14 | 10.1016/j.exer.2015.01.011 |
Identification and functional characterization of a GSH conjugate efflux pathway in the rat lens | Umapathy, A.| Li, B.| Donaldson, P.J.| Lim, J.C.-H. | 2015 | Investigative Ophthalmology and Visual Science | 4 | 10.1167/iovs.15-17109 |
Hippocampal lipid differences in Alzheimer's disease: a human brain study using matrix-assisted laser desorption/ionization-imaging mass spectrometry | Mendis, L.H.S.| Grey, A.C.| Faull, R.L.M.| Curtis, M.A. | 2016 | Brain and Behavior | 27 | 10.1002/brb3.517 |
Tools to fight the cataract epidemic: A review of experimental animal models that mimic age related nuclear cataract | Lim, J.C.| Umapathy, A.| Donaldson, P.J. | 2016 | Experimental Eye Research | 20 | 10.1016/j.exer.2015.09.007 |
Characterization of the effects of hyperbaric oxygen on the biochemical and optical properties of the bovine lens | Lim, J.C.| Vaghefi, E.| Li, B.| Nye-Wood, M.G.| Donaldson, P.J. | 2016 | Investigative Ophthalmology and Visual Science | 13 | 10.1167/iovs.16-19142 |
The phosphoinosotide 3-kinase catalytic subunit p110α is required for normal lens growth | Sellitto, C.| Li, L.| Vaghefi, E.| Donaldson, P.J.| Lin, R.Z.| White, T.W. | 2016 | Investigative Ophthalmology and Visual Science | 9 | 10.1167/iovs.16-19607 |
MALDI imaging of the eye: Mapping lipid, protein and metabolite distributions in aging and ocular disease | Grey, A.C. | 2016 | International Journal of Mass Spectrometry | 9 | 10.1016/j.ijms.2016.02.017 |
MALDI imaging mass spectrometry of Pacific White Shrimp L. vannamei and identification of abdominal muscle proteins | Schey, K.L.| Hachey, A.J.| Rose, K.L.| Grey, A.C. | 2016 | Proteomics | 7 | 10.1002/pmic.201500531 |
Review of the experimental background and implementation of computational models of the ocular lens microcirculation | Wu, H.-T.D.| Donaldson, P.J.| Vaghefi, E. | 2016 | IEEE Reviews in Biomedical Engineering | 3 | 10.1109/RBME.2016.2583404 |
Inside Front Cover: MALDI imaging mass spectrometry of Pacific White Shrimp L. vannamei and identification of abdominal muscle proteins | Schey, K.L.| Hachey, A.J.| Rose, K.L.| Grey, A.C. | 2016 | Proteomics | 1 | 10.1002/pmic.201670114 |
The physiological optics of the lens | Donaldson, P.J.| Grey, A.C.| Maceo Heilman, B.| Lim, J.C.| Vaghefi, E. | 2017 | Progress in Retinal and Eye Research | 60 | 10.1016/j.preteyeres.2016.09.002 |
The role of aquaporins in ocular lens homeostasis | Schey, K.L.| Petrova, R.S.| Gletten, R.B.| Donaldson, P.J. | 2017 | International Journal of Molecular Sciences | 21 | 10.3390/ijms18122693 |
Spatial distributions of glutathione and its endogenous conjugates in normal bovine lens and a model of lens aging | Nye-Wood, M.G.| Spraggins, J.M.| Caprioli, R.M.| Schey, K.L.| Donaldson, P.J.| Grey, A.C. | 2017 | Experimental Eye Research | 19 | 10.1016/j.exer.2016.11.008 |
Novel roles for the lens in preserving overall ocular health | Lim, J.C.| Umapathy, A.| Grey, A.C.| Vaghefi, E.| Donaldson, P.J. | 2017 | Experimental Eye Research | 14 | 10.1016/j.exer.2016.05.027 |
Comparison of the expression and spatial localization of glucose transporters in the rat, bovine and human lens | Lim, J.C.| Perwick, R.D.| Li, B.| Donaldson, P.J. | 2017 | Experimental Eye Research | 9 | 10.1016/j.exer.2017.06.012 |
The modulation of the phosphorylation status of NKCC1 in organ cultured bovine lenses: Implications for the regulation of fiber cell and overall lens volume | Vorontsova, I.| Donaldson, P.J.| Kong, Z.| Wickremesinghe, C.| Lam, L.| Lim, J.C. | 2017 | Experimental Eye Research | 5 | 10.1016/j.exer.2017.08.009 |
Fully automated laser ray tracing system to measure changes in the crystalline lens GRIN profile | Qiu, C.| Heilman, B.M.| Kaipio, J.| Donaldson, P.| Vaghefi, E. | 2017 | Biomedical Optics Express | 5 | 10.1364/BOE.8.004947 |
Regional differences in glutathione accumulation pathways in the rat cornea: Mapping of amino acid transporters involved in glutathione synthesis | Yoganandarajah, V.| Li, B.| Umapathy, A.| Donaldson, P.J.| Lim, J.C. | 2017 | Experimental Eye Research | 4 | 10.1016/j.exer.2017.04.002 |
Differential spread of anoxic depolarization contributes to the pattern of neuronal injury after oxygen and glucose deprivation (OGD) in the Substantia Nigra in rat brain slices | Karunasinghe, R.N.| Grey, A.C.| Telang, R.| Vlajkovic, S.M.| Lipski, J. | 2017 | Neuroscience | 3 | 10.1016/j.neuroscience.2016.10.067 |
Animal Models in Cataract Research | Lim, J.C.| Vorontsova, I.| Martis, R.M.| Donaldson, P.J. | 2017 | Animal Models for the Study of Human Disease: Second Edition | 1 | 10.1016/B978-0-12-809468-6.00004-8 |
The Effects of Maternal Under-Nutrition and a Post-Natal High Fat Diet on Lens Growth, Transparency and Oxidative Defense Systems in Rat Offspring | Jayaratne, S.K.| Donaldson, P.J.| Vickers, M.H.| Lim, J.C. | 2017 | Current Eye Research | 1 | 10.1080/02713683.2016.1214969 |
Drug delivery to the lens for the management of cataracts | Thrimawithana, T.R.| Rupenthal, I.D.| Räsch, S.S.| Lim, J.C.| Morton, J.D.| Bunt, C.R. | 2018 | Advanced Drug Delivery Reviews | 24 | 10.1016/j.addr.2018.03.009 |
Subventricular zone lipidomic architecture loss in Huntington's disease | Hunter, M.| Demarais, N.J.| Faull, R.L.M.| Grey, A.| Curtis, M.A. | 2018 | Journal of Neurochemistry | 19 | 10.1111/jnc.14468 |
Apparent Hyperthyroidism Caused by Biotin-Like Interference from IgM Anti-Streptavidin Antibodies | Lam, L.| Bagg, W.| Smith, G.| Chiu, W.W.| Middleditch, M.J.| Lim, J.C.-H.| Kyle, C.V. | 2018 | Thyroid | 14 | 10.1089/thy.2017.0673 |
Layer-specific lipid signatures in the human subventricular zone demonstrated by imaging mass spectrometry | Hunter, M.| Demarais, N.J.| Faull, R.L.M.| Grey, A.C.| Curtis, M.A. | 2018 | Scientific Reports | 13 | 10.1038/s41598-018-20793-4 |
Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance | Mountjoy, K.G.| Caron, A.| Hubbard, K.| Shome, A.| Grey, A.C.| Sun, B.| Bould, S.| Middleditch, M.| Pontré, B.| McGregor, A.| Harris, P.W.R.| Kowalczyk, R.| Brimble, M.A.| Botha, R.| Tan, K.M.L.| Piper, S.J.| Buchanan, C.| Lee, S.| Coll, A.P.| Elmquist, J.K. | 2018 | Molecular Metabolism | 13 | 10.1016/j.molmet.2017.11.008 |
Functional characterisation of glutathione export from the rat lens | Umapathy, A.| Li, B.| Donaldson, P.J.| Lim, J.C. | 2018 | Experimental Eye Research | 11 | 10.1016/j.exer.2017.10.010 |
The lens internal microcirculation system delivers solutes to the lens core faster than would be predicted by passive diffusion | Vaghefi, E.| Donaldson, P.J. | 2018 | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 10 | 10.1152/ajpregu.00180.2018 |
Dynamic functional contribution of the water channel AQP5 to the water permeability of peripheral lens fiber cells | Petrova, R.S.| Webb, K.F.| Vaghefi, E.| Walker, K.| Schey, K.L.| Donaldson, P.J. | 2018 | American Journal of Physiology - Cell Physiology | 8 | 10.1152/ajpcell.00214.2017 |
Nutritional strategies to prevent lens cataract: Current status and future strategies | Braakhuis, A.J.| Donaldson, C.I.| Lim, J.C.| Donaldson, P.J. | 2019 | Nutrients | 23 | 10.3390/nu11051186 |
The ciliary muscle and zonules of ZinN modulate lens intracellular hydrostatic pressure through transient receptor potential vanilloid channels | Chen, Y.| Gao, J.| Li, L.| Sellitto, C.| Mathias, R.T.| Donaldson, P.J.| White, T.W. | 2019 | Investigative Ophthalmology and Visual Science | 13 | 10.1167/iovs.19-27794 |
Verification and spatial mapping of TRPV1 and TRPV4 expression in the embryonic and adult mouse lens | Nakazawa, Y.| Donaldson, P.J.| Petrova, R.S. | 2019 | Experimental Eye Research | 12 | 10.1016/j.exer.2019.107707 |
A quantitative map of glutathione in the aging human lens | Grey, A.C.| Demarais, N.J.| West, B.J.| Donaldson, P.J. | 2019 | International Journal of Mass Spectrometry | 10 | 10.1016/j.ijms.2017.10.008 |
Distribution of small molecular weight drugs into the porcine lens: studies on imaging mass spectrometry, partition coefficients, and implications in ocular pharmacokinetics | Heikkinen, E.M.| Auriola, S.| Ranta, V.-P.| Demarais, N.J.| Grey, A.C.| Del Amo, E.M.| Toropainen, E.| Vellonen, K.-S.| Urtti, A.| Ruponen, M. | 2019 | Molecular Pharmaceutics | 10 | 10.1021/acs.molpharmaceut.9b00585 |
Development of an in vivo magnetic resonance imaging and computer modelling platform to investigate the physiological optics of the crystalline lens | Pan, X.| Lie, A.L.| White, T.W.| Donaldson, P.J.| Vaghefi, E. | 2019 | Biomedical Optics Express | 6 | 10.1364/BOE.10.004462 |
Mapping of the cystine–glutamate exchanger in the mouse eye: a role for xCT in controlling extracellular redox balance | Martis, R.M.| Donaldson, P.J.| Li, B.| Middleditch, M.| Kallingappa, P.K.| Lim, J.C. | 2019 | Histochemistry and Cell Biology | 6 | 10.1007/s00418-019-01805-4 |
Age-related spatial differences of human lens UV filters revealed by negative ion mode MALDI imaging mass spectrometry | Demarais, N.J.| Donaldson, P.J.| Grey, A.C. | 2019 | Experimental Eye Research | 5 | 10.1016/j.exer.2019.04.016 |
Age-dependent changes in glutathione metabolism pathways in the lens: New insights into therapeutic strategies to prevent cataract formation—A review | Lim, J.C.| Grey, A.C.| Zahraei, A.| Donaldson, P.J. | 2020 | Clinical and Experimental Ophthalmology | 16 | 10.1111/ceo.13801 |
MALDI imaging mass spectrometry of β- and γ-crystallins in the ocular lens | Anderson, D.M.| Nye-Wood, M.G.| Rose, K.L.| Donaldson, P.J.| Grey, A.C.| Schey, K.L. | 2020 | Journal of Mass Spectrometry | 12 | 10.1002/jms.4473 |
Detection of small molecule concentration gradients in ocular tissues and humours | Boughton, B.A.| Thomas, O.R.B.| Demarais, N.J.| Trede, D.| Swearer, S.E.| Grey, A.C. | 2020 | Journal of Mass Spectrometry | 8 | 10.1002/jms.4460 |
Proinflammatory cytokines trigger biochemical and neurochemical changes in mouse retinal explants exposed to hyperglycemic conditions | Shivashankar, G.| Lim, J.C.| Acosta, M.L. | 2020 | Molecular Vision | 7 | - |
Changes to zonular tension alters the subcellular distribution of AQP5 in regions of influx and efflux of water in the rat lens | Petrova, R.S.| Bavana, N.| Zhao, R.| Schey, K.L.| Donaldson, P.J. | 2020 | Investigative Ophthalmology and Visual Science | 6 | 10.1167/iovs.61.11.36 |
Multi-parametric MRI of the physiology and optics of the in-vivo mouse lens | Muir, E.R.| Pan, X.| Donaldson, P.J.| Vaghefi, E.| Jiang, Z.| Sellitto, C.| White, T.W. | 2020 | Magnetic Resonance Imaging | 4 | 10.1016/j.mri.2020.04.015 |
Vitamin C and the lens: New insights into delaying the onset of cataract | Lim, J.C.| Arredondo, M.C.| Braakhuis, A.J.| Donaldson, P.J. | 2020 | Nutrients | 3 | 10.3390/nu12103142 |
Characterisation of glutathione export from human donor lenses | Li, B.| Kim, J.-Y.| Martis, R.M.| Donaldson, P.J.| Lim, J.C. | 2020 | Translational Vision Science and Technology | 3 | 10.1167/TVST.9.8.37 |
Identification, Expression, and Roles of the Cystine/Glutamate Antiporter in Ocular Tissues | Martis, R.M.| Knight, L.J.| Donaldson, P.J.| Lim, J.C. | 2020 | Oxidative Medicine and Cellular Longevity | 3 | 10.1155/2020/4594606 |
Using the lens paradox to optimize an in vivo mri-based optical model of the aging human crystalline lens | Lie, A.L.| Pan, X.| White, T.W.| Donaldson, P.J.| Vaghefi, E. | 2020 | Translational Vision Science and Technology | 2 | 10.1167/TVST.9.8.39 |
Corneal opacities in mice exposed to repeated contact procedures during ocular examinations | Martis, R.M.| Donaldson, P.J.| Lim, J.C. | 2020 | Clinical and Experimental Optometry | 2 | 10.1111/cxo.12934 |