Repository

TitleAuthorsYearJournalCitationsDOI
Visualizing ocular lens fluid dynamics using MRI: Manipulation of steady state water content and water fluxesVaghefi, E.| Pontre, B.P.| Jacobs, M.D.| Donaldson, P.J.2011American Journal of Physiology - Regulatory Integrative and Comparative Physiology4810.1152/ajpregu.00173.2011
Spatial localization of A2E in the retinal pigment epitheliumGrey, A.C.| Crouch, R.K.| Koutalos, Y.| Schey, K.L.| Ablonczy, Z.2011Investigative Ophthalmology and Visual Science4410.1167/iovs.10-7020
Focus on Molecules: The cystine/glutamate exchanger (System xc-)Lim, J.C.| Donaldson, P.J.2011Experimental Eye Research2310.1016/j.exer.2010.05.007
Cryptococcus neoformans modulates extracellular killing by neutrophilsQureshi, A.| Grey, A.| Rose, K.L.| Schey, K.L.| Del Poeta, M.2011Frontiers in Microbiology1410.3389/fmicb.2011.00193
Cellular localization of glutamate and glutamine metabolism and transport pathways in the rat ciliary epitheliumHu, R.G.| Lim, J.C.| Kalloniatis, M.| Donaldson, P.J.2011Investigative Ophthalmology and Visual Science810.1167/iovs.10-6422
Fatty acid uptake and incorporation into phospholipids in the rat lensNealon, J.R.| Blanksby, S.J.| Donaldson, P.J.| Truscott, R.J.W.| Mitchell, T.W.2011Investigative Ophthalmology and Visual Science210.1167/iovs.10-5830
Magnetic resonance and confocal imaging of solute penetration into the lens reveals a zone of restricted extracellular space diffusionVaghefi, E.| Walker, K.| Pontre, B.P.| Jacobs, M.D.| Donaldson, P.J.2012American Journal of Physiology - Regulatory Integrative and Comparative Physiology2510.1152/ajpregu.00611.2011
Characterization of glutathione uptake, synthesis, and efflux pathways in the epithelium and endothelium of the rat corneaLi, B.| Lee, M.S.| Lee, R.S.Y.| Donaldson, P.J.| Lim, J.C.2012Cornea1810.1097/ICO.0b013e31823f76bd
Molecule-specific imaging and quantitation of A2E in the RPEAblonczy, Z.| Gutierrez, D.B.| Grey, A.C.| Schey, K.L.| Crouch, R.K.2012Advances in Experimental Medicine and Biology1510.1007/978-1-4614-0631-0_11
Development of a 3D finite element model of lens microcirculationVaghefi, E.| Malcolm, D.T.K.| Jacobs, M.D.| Donaldson, P.J.2012BioMedical Engineering Online1010.1186/1475-925X-11-69
Alterations of glutamate, glutamine, and related amino acids in the anterior eye secondary to ischaemia and reperfusionHu, R.G.| Zhu, Y.| Donaldson, P.| Kalloniatis, M.2012Current Eye Research610.3109/02713683.2012.669509
Identification of a nonselective cation channel in isolated lens fiber cells that is activated by cell shrinkageGunning, S.J.| Chung, K.K.H.| Donaldson, P.J.| Webb, K.F.2012American Journal of Physiology - Cell Physiology410.1152/ajpcell.00237.2012
Fluid in equals fluid out-evidence for circulating fluid fluxes in the lensDonaldson, P.J.2012Investigative Ophthalmology and Visual Science110.1167/iovs.12-11012
Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epitheliumAblonczy, Z.| Higbee, D.| Anderson, D.M.| Dahrouj, M.| Grey, A.C.| Gutierrez, D.| Koutalos, Y.| Schey, K.L.| Hanneken, A.| Crouch, R.K.2013Investigative Ophthalmology and Visual Science10310.1167/iovs.13-12250
Antioxidant delivery pathways in the anterior eyeUmapathy, A.| Donaldson, P.| Lim, J.2013BioMed Research International3010.1155/2013/207250
Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epitheliumAblonczy, Z.| Higbee, D.| Grey, A.C.| Koutalos, Y.| Schey, K.L.| Crouch, R.K.2013Archives of Biochemistry and Biophysics2710.1016/j.abb.2013.08.005
Mass spectrometry of membrane proteins: A focus on aquaporinsSchey, K.L.| Grey, A.C.| Nicklay, J.J.2013Biochemistry2610.1021/bi301604j
Verification and spatial localization of aquaporin-5 in the ocular lensGrey, A.C.| Walker, K.L.| Petrova, R.S.| Han, J.| Wilmarth, P.A.| David, L.L.| Donaldson, P.J.| Schey, K.L.2013Experimental Eye Research2210.1016/j.exer.2012.12.004
Molecular identification and cellular localization of a potential transport system involved in cystine/cysteine uptake in human lensesLim, J.C.| Lam, L.| Li, B.| Donaldson, P.J.2013Experimental Eye Research2010.1016/j.exer.2013.09.002
A computer model of lens structure and function predicts experimental changes to steady state properties and circulating currentsVaghefi, E.| Liu, N.| Donaldson, P.J.2013BioMedical Engineering Online1110.1186/1475-925X-12-85
Molecular identification and cellular localisation of GSH synthesis, uptake, efflux and degradation pathways in the rat ciliary bodyLi, B.| Umapathy, A.| Tran, L.U.| Donaldson, P.J.| Lim, J.C.2013Histochemistry and Cell Biology1110.1007/s00418-012-1049-6
An exploration into diffusion tensor imaging in the bovine ocular lensVaghefi, E.| Donaldson, P.J.2013Frontiers in Physiology610.3389/fphys.2013.00033
A link between maternal malnutrition and depletion of glutathione in the developing lens: A possible explanation for idiopathic childhood cataract?Kumar, D.| Lim, J.C.| Donaldson, P.J.2013Clinical and Experimental Optometry410.1111/cxo.12076
Reversing the age-dependent decline in lens transport: A new strategy to prevent age related nuclear cataract?Donaldson, P.2013Investigative Ophthalmology and Visual Science210.1167/iovs.13-13394
Alzheimer's disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkersChang, L.Y.L.| Lowe, J.| Ardiles, A.| Lim, J.| Grey, A.C.| Robertson, K.| Danesh-Meyer, H.| Palacios, A.G.| Acosta, M.L.2014Alzheimer's and Dementia6310.1016/j.jalz.2013.06.004
The utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometryAblonczy, Z.| Smith, N.| Anderson, D.M.| Grey, A.C.| Spraggins, J.| Koutalos, Y.| Schey, K.L.| Crouch, R.K.2014Proteomics1910.1002/pmic.201300406
Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lensesVorontsova, I.| Lam, L.| Delpire, E.| Lim, J.| Donaldson, P.2014Investigative Ophthalmology and Visual Science510.1167/iovs.14-15911
Active maintenance of the gradient of refractive index is required to sustain the optical properties of the lensVaghefi, E.| Kim, A.| Donaldson, P.J.2015Investigative Ophthalmology and Visual Science2610.1167/iovs.15-17861
Spatial distributions of AQP5 and AQP0 in embryonic and postnatal mouse lens developmentPetrova, R.S.| Schey, K.L.| Donaldson, P.J.| Grey, A.C.2015Experimental Eye Research1410.1016/j.exer.2015.01.011
Identification and functional characterization of a GSH conjugate efflux pathway in the rat lensUmapathy, A.| Li, B.| Donaldson, P.J.| Lim, J.C.-H.2015Investigative Ophthalmology and Visual Science410.1167/iovs.15-17109
Hippocampal lipid differences in Alzheimer's disease: a human brain study using matrix-assisted laser desorption/ionization-imaging mass spectrometryMendis, L.H.S.| Grey, A.C.| Faull, R.L.M.| Curtis, M.A.2016Brain and Behavior2710.1002/brb3.517
Tools to fight the cataract epidemic: A review of experimental animal models that mimic age related nuclear cataractLim, J.C.| Umapathy, A.| Donaldson, P.J.2016Experimental Eye Research2010.1016/j.exer.2015.09.007
Characterization of the effects of hyperbaric oxygen on the biochemical and optical properties of the bovine lensLim, J.C.| Vaghefi, E.| Li, B.| Nye-Wood, M.G.| Donaldson, P.J.2016Investigative Ophthalmology and Visual Science1310.1167/iovs.16-19142
The phosphoinosotide 3-kinase catalytic subunit p110α is required for normal lens growthSellitto, C.| Li, L.| Vaghefi, E.| Donaldson, P.J.| Lin, R.Z.| White, T.W.2016Investigative Ophthalmology and Visual Science910.1167/iovs.16-19607
MALDI imaging of the eye: Mapping lipid, protein and metabolite distributions in aging and ocular diseaseGrey, A.C.2016International Journal of Mass Spectrometry910.1016/j.ijms.2016.02.017
MALDI imaging mass spectrometry of Pacific White Shrimp L. vannamei and identification of abdominal muscle proteinsSchey, K.L.| Hachey, A.J.| Rose, K.L.| Grey, A.C.2016Proteomics710.1002/pmic.201500531
Review of the experimental background and implementation of computational models of the ocular lens microcirculationWu, H.-T.D.| Donaldson, P.J.| Vaghefi, E.2016IEEE Reviews in Biomedical Engineering310.1109/RBME.2016.2583404
Inside Front Cover: MALDI imaging mass spectrometry of Pacific White Shrimp L. vannamei and identification of abdominal muscle proteinsSchey, K.L.| Hachey, A.J.| Rose, K.L.| Grey, A.C.2016Proteomics110.1002/pmic.201670114
The physiological optics of the lensDonaldson, P.J.| Grey, A.C.| Maceo Heilman, B.| Lim, J.C.| Vaghefi, E.2017Progress in Retinal and Eye Research6010.1016/j.preteyeres.2016.09.002
The role of aquaporins in ocular lens homeostasisSchey, K.L.| Petrova, R.S.| Gletten, R.B.| Donaldson, P.J.2017International Journal of Molecular Sciences2110.3390/ijms18122693
Spatial distributions of glutathione and its endogenous conjugates in normal bovine lens and a model of lens agingNye-Wood, M.G.| Spraggins, J.M.| Caprioli, R.M.| Schey, K.L.| Donaldson, P.J.| Grey, A.C.2017Experimental Eye Research1910.1016/j.exer.2016.11.008
Novel roles for the lens in preserving overall ocular healthLim, J.C.| Umapathy, A.| Grey, A.C.| Vaghefi, E.| Donaldson, P.J.2017Experimental Eye Research1410.1016/j.exer.2016.05.027
Comparison of the expression and spatial localization of glucose transporters in the rat, bovine and human lensLim, J.C.| Perwick, R.D.| Li, B.| Donaldson, P.J.2017Experimental Eye Research910.1016/j.exer.2017.06.012
The modulation of the phosphorylation status of NKCC1 in organ cultured bovine lenses: Implications for the regulation of fiber cell and overall lens volumeVorontsova, I.| Donaldson, P.J.| Kong, Z.| Wickremesinghe, C.| Lam, L.| Lim, J.C.2017Experimental Eye Research510.1016/j.exer.2017.08.009
Fully automated laser ray tracing system to measure changes in the crystalline lens GRIN profileQiu, C.| Heilman, B.M.| Kaipio, J.| Donaldson, P.| Vaghefi, E.2017Biomedical Optics Express510.1364/BOE.8.004947
Regional differences in glutathione accumulation pathways in the rat cornea: Mapping of amino acid transporters involved in glutathione synthesisYoganandarajah, V.| Li, B.| Umapathy, A.| Donaldson, P.J.| Lim, J.C.2017Experimental Eye Research410.1016/j.exer.2017.04.002
Differential spread of anoxic depolarization contributes to the pattern of neuronal injury after oxygen and glucose deprivation (OGD) in the Substantia Nigra in rat brain slicesKarunasinghe, R.N.| Grey, A.C.| Telang, R.| Vlajkovic, S.M.| Lipski, J.2017Neuroscience310.1016/j.neuroscience.2016.10.067
Animal Models in Cataract ResearchLim, J.C.| Vorontsova, I.| Martis, R.M.| Donaldson, P.J.2017Animal Models for the Study of Human Disease: Second Edition110.1016/B978-0-12-809468-6.00004-8
The Effects of Maternal Under-Nutrition and a Post-Natal High Fat Diet on Lens Growth, Transparency and Oxidative Defense Systems in Rat OffspringJayaratne, S.K.| Donaldson, P.J.| Vickers, M.H.| Lim, J.C.2017Current Eye Research110.1080/02713683.2016.1214969
Drug delivery to the lens for the management of cataractsThrimawithana, T.R.| Rupenthal, I.D.| Räsch, S.S.| Lim, J.C.| Morton, J.D.| Bunt, C.R.2018Advanced Drug Delivery Reviews2410.1016/j.addr.2018.03.009
Subventricular zone lipidomic architecture loss in Huntington's diseaseHunter, M.| Demarais, N.J.| Faull, R.L.M.| Grey, A.| Curtis, M.A.2018Journal of Neurochemistry1910.1111/jnc.14468
Apparent Hyperthyroidism Caused by Biotin-Like Interference from IgM Anti-Streptavidin AntibodiesLam, L.| Bagg, W.| Smith, G.| Chiu, W.W.| Middleditch, M.J.| Lim, J.C.-H.| Kyle, C.V.2018Thyroid1410.1089/thy.2017.0673
Layer-specific lipid signatures in the human subventricular zone demonstrated by imaging mass spectrometryHunter, M.| Demarais, N.J.| Faull, R.L.M.| Grey, A.C.| Curtis, M.A.2018Scientific Reports1310.1038/s41598-018-20793-4
Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balanceMountjoy, K.G.| Caron, A.| Hubbard, K.| Shome, A.| Grey, A.C.| Sun, B.| Bould, S.| Middleditch, M.| Pontré, B.| McGregor, A.| Harris, P.W.R.| Kowalczyk, R.| Brimble, M.A.| Botha, R.| Tan, K.M.L.| Piper, S.J.| Buchanan, C.| Lee, S.| Coll, A.P.| Elmquist, J.K.2018Molecular Metabolism1310.1016/j.molmet.2017.11.008
Functional characterisation of glutathione export from the rat lensUmapathy, A.| Li, B.| Donaldson, P.J.| Lim, J.C.2018Experimental Eye Research1110.1016/j.exer.2017.10.010
The lens internal microcirculation system delivers solutes to the lens core faster than would be predicted by passive diffusionVaghefi, E.| Donaldson, P.J.2018American Journal of Physiology - Regulatory Integrative and Comparative Physiology1010.1152/ajpregu.00180.2018
Dynamic functional contribution of the water channel AQP5 to the water permeability of peripheral lens fiber cellsPetrova, R.S.| Webb, K.F.| Vaghefi, E.| Walker, K.| Schey, K.L.| Donaldson, P.J.2018American Journal of Physiology - Cell Physiology810.1152/ajpcell.00214.2017
Nutritional strategies to prevent lens cataract: Current status and future strategiesBraakhuis, A.J.| Donaldson, C.I.| Lim, J.C.| Donaldson, P.J.2019Nutrients2310.3390/nu11051186
The ciliary muscle and zonules of ZinN modulate lens intracellular hydrostatic pressure through transient receptor potential vanilloid channelsChen, Y.| Gao, J.| Li, L.| Sellitto, C.| Mathias, R.T.| Donaldson, P.J.| White, T.W.2019Investigative Ophthalmology and Visual Science1310.1167/iovs.19-27794
Verification and spatial mapping of TRPV1 and TRPV4 expression in the embryonic and adult mouse lensNakazawa, Y.| Donaldson, P.J.| Petrova, R.S.2019Experimental Eye Research1210.1016/j.exer.2019.107707
A quantitative map of glutathione in the aging human lensGrey, A.C.| Demarais, N.J.| West, B.J.| Donaldson, P.J.2019International Journal of Mass Spectrometry1010.1016/j.ijms.2017.10.008
Distribution of small molecular weight drugs into the porcine lens: studies on imaging mass spectrometry, partition coefficients, and implications in ocular pharmacokineticsHeikkinen, E.M.| Auriola, S.| Ranta, V.-P.| Demarais, N.J.| Grey, A.C.| Del Amo, E.M.| Toropainen, E.| Vellonen, K.-S.| Urtti, A.| Ruponen, M.2019Molecular Pharmaceutics1010.1021/acs.molpharmaceut.9b00585
Development of an in vivo magnetic resonance imaging and computer modelling platform to investigate the physiological optics of the crystalline lensPan, X.| Lie, A.L.| White, T.W.| Donaldson, P.J.| Vaghefi, E.2019Biomedical Optics Express610.1364/BOE.10.004462
Mapping of the cystine–glutamate exchanger in the mouse eye: a role for xCT in controlling extracellular redox balanceMartis, R.M.| Donaldson, P.J.| Li, B.| Middleditch, M.| Kallingappa, P.K.| Lim, J.C.2019Histochemistry and Cell Biology610.1007/s00418-019-01805-4
Age-related spatial differences of human lens UV filters revealed by negative ion mode MALDI imaging mass spectrometryDemarais, N.J.| Donaldson, P.J.| Grey, A.C.2019Experimental Eye Research510.1016/j.exer.2019.04.016
Age-dependent changes in glutathione metabolism pathways in the lens: New insights into therapeutic strategies to prevent cataract formation—A reviewLim, J.C.| Grey, A.C.| Zahraei, A.| Donaldson, P.J.2020Clinical and Experimental Ophthalmology1610.1111/ceo.13801
MALDI imaging mass spectrometry of β- and γ-crystallins in the ocular lensAnderson, D.M.| Nye-Wood, M.G.| Rose, K.L.| Donaldson, P.J.| Grey, A.C.| Schey, K.L.2020Journal of Mass Spectrometry1210.1002/jms.4473
Detection of small molecule concentration gradients in ocular tissues and humoursBoughton, B.A.| Thomas, O.R.B.| Demarais, N.J.| Trede, D.| Swearer, S.E.| Grey, A.C.2020Journal of Mass Spectrometry810.1002/jms.4460
Proinflammatory cytokines trigger biochemical and neurochemical changes in mouse retinal explants exposed to hyperglycemic conditionsShivashankar, G.| Lim, J.C.| Acosta, M.L.2020Molecular Vision7-
Changes to zonular tension alters the subcellular distribution of AQP5 in regions of influx and efflux of water in the rat lensPetrova, R.S.| Bavana, N.| Zhao, R.| Schey, K.L.| Donaldson, P.J.2020Investigative Ophthalmology and Visual Science610.1167/iovs.61.11.36
Multi-parametric MRI of the physiology and optics of the in-vivo mouse lensMuir, E.R.| Pan, X.| Donaldson, P.J.| Vaghefi, E.| Jiang, Z.| Sellitto, C.| White, T.W.2020Magnetic Resonance Imaging410.1016/j.mri.2020.04.015
Vitamin C and the lens: New insights into delaying the onset of cataractLim, J.C.| Arredondo, M.C.| Braakhuis, A.J.| Donaldson, P.J.2020Nutrients310.3390/nu12103142
Characterisation of glutathione export from human donor lensesLi, B.| Kim, J.-Y.| Martis, R.M.| Donaldson, P.J.| Lim, J.C.2020Translational Vision Science and Technology310.1167/TVST.9.8.37
Identification, Expression, and Roles of the Cystine/Glutamate Antiporter in Ocular TissuesMartis, R.M.| Knight, L.J.| Donaldson, P.J.| Lim, J.C.2020Oxidative Medicine and Cellular Longevity310.1155/2020/4594606
Using the lens paradox to optimize an in vivo mri-based optical model of the aging human crystalline lensLie, A.L.| Pan, X.| White, T.W.| Donaldson, P.J.| Vaghefi, E.2020Translational Vision Science and Technology210.1167/TVST.9.8.39
Corneal opacities in mice exposed to repeated contact procedures during ocular examinationsMartis, R.M.| Donaldson, P.J.| Lim, J.C.2020Clinical and Experimental Optometry210.1111/cxo.12934